In addition to the episode count, the cast of the series is also revealed. The series will star Ryohei Kimura (Kuroko's Basketball) as Shinjiro Hayata/ULTRAMAN, a role that he will reprise from the motion comic adaptation. Also part of the show's cast are:
- Takuya Eguchi (Ore Monogatari!) as Dan Moroboshi/SEVEN
- Megumi Han (Hunter x Hunter, Shuriken Sentai Ninninger) as Seiji Hokuto/ACE, making this her second role in a Tsuburaya production, the first being Ultraman Geed's Pega
- Hideyuki Tanaka (One Piece) as Shin Hayata/original Ultraman, the actor is also the current voice of the original Ultraman's senior, Zoffy since Ultraman Mebius
The project will be directed by Kenji Kamiyama (Ghost in the Shell: Stand Alone Complex) and Shinji Aramaki (Appleseed) with Production I.G (Ghost in the Shell: Stand Alone Complex) and Sola Digital Arts (Appleseed Alpha) producing this 3D CG anime. Lastly, it will feature music from Metal Gear Solid's Nobuko Toda and Kazuma Jinnouchi.