- Alexander Maniatis (Warrior) as Klahadore/Kuro
- Steven Ward (House on Willow Street) as Dracule Mihawk
- Craig Fairbrass (EastEnders) as Chef Zeff
- Langley Kirkwood (Mia and the White Lion) as Captain Morgan
- Celeste Loots (Sporadies Nomadies) as Kaya
- Chioma Umeala (Isono) as Nojiko
One Piece is a co-production between Netflix and Tomorrow Studios, with Netflix handling physical production.